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Biology ProgramBiology: Aquatic Science ConcentrationBiology: Cellular & Molecular Concentration Biology: Environmental Science ConcentrationBiology: Physiology ConcentrationDirector: Anita Baines4032 Cowley Hall; 608.785.8239Email:Biology: Nurse Anesthesia Concentration School of Anesthesia Program Director: Jessica PetersonMayo Clinic Health System Franciscan Healthcare608.785.0940 ext. 2-2428Email:The Master of Science in Biology Program is a multi-disciplinary program that allows students advanced study in several traditional and non-traditional areas of biology. Students have the option of a general M.S. Degree in biology (Build your own degree!) or may obtain an M.S. Degree in biology with a formal concentration in aquatic science, cellular and molecular biology, nurse anesthesia, environmental science, or physiology.Admission to the program is based, in part, on undergraduate grade point average (GPA), scores on the GRE general exam, letters of recommendation, and on individually prescribed undergraduate course work to meet prerequisite requirements for each concentration.

Each student will choose a major advisor and an advisory committee during the first semester of residence. This committee will assist the student in drafting the student’s plan of study, which will dictate the student’s curriculum for the ensuing semesters.All students complete a capstone experience. Students in the general M.S.

Option and in all but one of the concentrations complete a thesis or seminar paper. Students obtaining the M.S. In biology with a nurse anesthesia concentration instead complete extensive clinical training in affiliation with Mayo Clinic Health System - Franciscan Healthcare, and most will go on to complete additional advanced degree coursework with Viterbo University.

The following is the graduate faculty as of the publication date of this catalog. This list will not be updated again until the next catalog is published in June. ProfessorScott CooperDaniel (Tim) GerberRick GillisRoger HaroTisha King-HeidenSumei LiuMargaret (Peg) MaherJennifer MiskowskiGregory SandlandEric StraussMeredith ThomsenThomas Volk Associate ProfessorMichael AblerAnita BainesAnne GalbraithBarrett KleinJennifer KleinMegan LitsterTodd OsmundsonAnton SanderfootBradley SeebachEric Snively Assistant ProfessorSierra ColavitoElizabeth PeitzmanDavid SchumannChristine SchwartzJaclyn WisinskiAlder YuMary Zimmerman. BIO 401/501 Cr.4Comparative Vertebrate AnatomyComparative anatomy is fundamental for investigating vertebrate function and evolutionary biology. The course integrates anatomy, evolution, and development of the chordate body, system-by-system and across the group's diversity from flying and running vertebrates to sea squirts and lampreys.

Labs will raise insight and skill through comprehensive, respectful dissection of minks, dogfish sharks, lampreys, and representative organ specimens. One lab period per week is dedicated to a main dissection and exploration of anatomy. The next lab period integrates lecture, dissection refinement, and collaborative reinforcement of learning.

This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Offered Spring. BIO 408/508 Cr.4Developmental BiologyAn exploration of the cellular and molecular mechanisms that underlie embryonic development in several model organisms. Topics include fertilization, regulation of gene expression, cell fate determination, stem cells, early pattern formation, morphogenesis of tissues/organs, and limb formation.

The course primarily focuses on animal models with an emphasis on evolutionarily conserved processes, structures, and molecular pathways. Technological advances and relevance to human development and disease are highlighted throughout. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: or or; or;. Offered Spring.

BIO/PAS/PTS 509 Cr.3Human Gross AnatomyA comprehensive consideration of human gross anatomy. Systems included are musculoskeletal, neurological, urogenital, gastrointestinal and cardiopulmonary. Function, development, and topographic correlations are emphasized as a means toward evaluating clinical applications.

Biomechanical function, topographic and clinical applications are emphasized. Prerequisite: admission to the Biology CRNA Program, PAS Program, or DPT Professional Program; concurrent enrollment in BIO/PAS/ under same department.

(Cross-listed with BIO/PAS/PTS; may only earn credit in one department.) Offered Summer. BIO/PAS/PTS 510 Cr.3Applied Human Gross AnatomyA comprehensive consideration of human anatomy including both neuro-musculoskeletal components and internal organ systems. Systems included are musculoskeletal, neurological, urogenital, gastrointestinal, and cardiopulmonary. The course provides an in-depth understanding of the gross anatomy of the human body through regional dissection. This understanding will then be demonstrated through the application of anatomy within clinical presentations.

Prerequisite: admission to the Biology CRNA Program, PAS Program, or DPT Professional Program; concurrent enrollment in BIO/PAS/ under same department. (Cross-listed with BIO/PAS/PTS; may only earn credit in one department.) Offered Summer. BIO 412/512 Cr.4MycologyA survey of all the major groups of fungi of the fungal kingdom (and relatives) in terms of systematics, anatomy, morphology, ecology, physiology, genetics, evolutionary relationships, and human and plant pathology.

Laboratory includes microscopic and macroscopic study of the fungi, as well as making a collection of cultures and of fungal reproductive structures (including mushrooms) from selected groups. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Both the microbiology course and one of the biology courses are strongly recommended.

Offered Fall. BIO 414/514 Cr.3Freshwater Invertebrate ZoologyIntroduces the ecology and taxonomy of the metazoan, non-parasitic freshwater invertebrates. An extensive course designed to provide a foundation for taxonomic knowledge, and basic understanding of the biology and ecology of freshwater invertebrates for advanced students in aquatic and environmental sciences. Lectures will focus on ecology; labs on taxonomy and quantitative skills. A student reference collection and weekend field trips will be required. Offered Occasionally. BIO 419/519 Cr.3Quantitative Methods in EcologyAn introduction to field and laboratory procedures used by ecologists to describe and analyze the interactions between organisms and their environments.

The course will emphasize quantitative techniques, including the use of computer technology, for collecting, recording and interpreting ecological data. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations.

Prerequisite:, or equivalent coursework;, or equivalent experience with statistics. Offered Fall.

BIO 421/521 Cr.3Comparative Vertebrate EndocrinologyA comprehensive study of the production, regulation, structure, molecular to whole-body actions, metabolism, and excretion of biochemical signaling molecules across vertebrates with a focus on amphibians, fish, birds, and mammals. Hormone and neurotransmitter pathways will be examined with relationship to evolutionary and environmental influences using lecture, review of primary literature, and case studies. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: or /558. Offered Spring. BIO 424/524 Cr.3Human EndocrinologyA comprehensive study of the production, regulation, structure, molecular to whole body actions, metabolism, and excretion of biochemical signaling molecules in humans.

The classical and more recently recognized neurotransmitter and hormone pathways and clinical and pharmacology considerations of each will be explored with lectures, primary literature and case studies. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite:, /558, or equivalent coursework.

Offered Fall. BIO 432/532 Cr.2Biology of CancerA survey of the current knowledge of cancer biology. The course will include lectures on a wide range of cancer topics including: characteristics of cancer cells, carcinogenesis, cancer genes, tumor classification, invasion, metastasis, inheritance, immunology, drug development, treatment, and prevention. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: or;. Offered Fall, Spring.

BIO 435/535 Cr.3Molecular BiologyA study of molecular biology with an emphasis on eukaryotic systems. The course will focus on the molecular aspects controlling biological processes. The impact of recombinant DNA technology on biotechnology and medicine will also be examined. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: and, or /516; three semesters of college chemistry including organic chemistry.

Biochemistry strongly recommended. /536 is an optional laboratory which can be taken concurrently. Offered Fall, Spring. BIO 436/536 Cr.1Molecular Biology LaboratoryA study of molecular biology with an emphasis on eukaryotic systems.

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Laboratory emphasis is on recombinant DNA technology, current techniques used to express recombinant proteins in eukaryotic cells, computer based DNA analysis, macromolecular modeling using computers, and quantitative assay techniques. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: taken concurrently with /535.

This lab is optional for those enrolled in /535. Offered Fall, Spring. BIO/MIC 440/540 Cr.2BioinformaticsIn this course, students will use computers to study and compare the sequence of nucleotides in DNA or RNA, or the amino acids in a protein. Computers also are used to examine the three dimensional structure of protein. Being able to manipulate and study this information is the basis for the current revolution in biotechnology. Topics include evolution, taxonomy, genomics and understanding disease.

This course provides students an opportunity to explore the relationships between biology, microbiology, chemistry, and computer science. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: or /516. (Cross-listed with BIO/MIC; may only earn credit in one department.) Offered Spring, Winter. BIO 441/541 Cr.3Environmental ToxicologyThe study of the lethal and sublethal effects of chemical contaminants on ecosystems and humans. Topics covered include environmental legislation, chemical distribution and fate in the environment, methods of toxicity testing, assessment of exposure and risk, effects of chemical contaminants on humans, and fish and wildlife populations, communities and ecosystems, and toxicity of specific chemical groups.

This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: or;. Offered Spring - Odd Numbered Years.

BIO/MIC 442/542 Cr.3Plant Microbe InteractionsThis course will explore in-depth various ways that plants interact with microbes in the environment, at the macroscopic, cellular, and molecular levels. Case studies will include both parasitic and mutualistic (symbiotic) interactions. Microbes include fungi, bacteria, nematodes, and viruses. Includes plant pathology and studies of the beneficial relationships between plants and microbes. Inquiry-based labs are integrated into the lecture and discussion sessions. This course is taught largely at an undergraduate level.

Graduate students will have additional course requirements/expectations. Prerequisite: or;. (Cross-listed with BIO/MIC; may only earn credit in one department.) Offered Fall - Odd Numbered Years.

BIO 443/543 Cr.3Molecular Mechanism of Disease and Drug ActionA survey of the leading non-infectious and non-cancerous diseases in the industrialized world. This course will explore the molecular mechanisms of disease, clinical symptomology, and pharmacological treatment. Students will be expected to conduct thorough research on a given disease and present their results in a poster session. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Offered Spring. BIO 444/544 Cr.4EntomologyInsects and their close relatives are ubiquitous, affecting humans' lives in profound ways.

We will investigate the anatomy, behavior, evolution, and ecology of insects, as well as how insects impact human culture. Discussions, presentations, illustrations, field research, curation of specimens, and other activities offer opportunities for students to apply insect research knowledge and skills. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Offered Fall - Even Numbered Years. BIO 546 Cr.3Animal BehaviorWe will explore factors that help to explain how and why animals behave as they do.

Example topics include social behavior, learning, symbiotic relationships, sensory systems, communication, mating systems, defense, and parental care. Emphasis will be placed on non-human animals. Discussions, presentations, illustrations, and other activities offer opportunities for students to apply behavioral research knowledge and skills. This course is taught largely at an undergraduate level.

Graduate students will have additional course requirements/expectations. Offered Annually. BIO 447/547 Cr.3Standard Methods/Quality Assurance Water AnalysesThis course will instruct students on the use of standard methods for analyses of selected biological, chemical, and physical constituents commonly included in water quality analyses.

Quality assurance procedures, including Good Laboratory Practice Standards (GLPS) will be integrated into all activities. Materials covered include: principles of methods used; evaluation of precision, bias, and contamination; proper reporting and interpretation of results; and environmental sources and significance of constituents analyzed.

This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Prerequisite: or or or, and three semesters of college chemistry.

Offered Spring. BIO 449/549 Cr.3Advanced Microscopy and Biological ImagingPrinciples and techniques used in modern microscopy and biological image analysis.

Emphasis will be on student projects to become proficient at confocal, fluorescence, and scanning electron microscopy. Students will also learn specimen preparation, digital imaging, and image processing and analysis for biological applications. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Offered Fall - Even Numbered Years.

BIO 456/556 Cr.4Plant EcologyConservation biology, ecological restoration, and predicting the effects of climate change all require an understanding of plant ecology. This course is focused on the interactions among plants, other organisms, and the environment. We will work across the individual, population, and community levels, and emphasize an exploratory approach to plant ecology. Class activities will include lectures, the discussion of ecological journal articles, and carrying out student-designed experiments.

This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Offered Fall - Even Numbered Years. BIO 458/558 Cr.4Comparative Animal PhysiologyThis course has both a lecture and a laboratory component. It aims to provide a thorough understanding of animal physiology from a comparative perspective. Emphasis will be placed on the basic physiological principles by which animals perform their life sustaining functions.

Lectures will focus on vertebral animals, but will span both invertebrate and vertebrate models to illustrate how largely divergent groups have evolved different (or similar) mechanisms to cope with environmental challenges. The laboratory component will provide an active learning environment and hands-on experience in physiological experimentation. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations.

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Offered Fall. BIO 460/560 Cr.1-4Symposium in BiologyStudies in biology of interest to specific groups.

Varying topics will be offered at intervals with a specific title assigned to each. May be staffed by resident faculty or visiting lecturers. Other departments may be invited to participate. This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations. Repeatable for credit - maximum 16. Variable offerings - check registration schedules.

Prerequisite: four semesters of biology. Offered Occasionally.

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BIO 464/564 Cr.3Stream and Watershed EcologyIntroduces key concepts and theory pertinent to understanding and managing fluvial ecosystems (rivers and streams) and their watersheds. The course will emphasize rivers as large-scale physical and biological systems. Course work includes a comparative case study of distinctive types of temperate, tropical, and polar rivers.

This course is taught largely at an undergraduate level. Graduate students will have additional course requirements/expectations.

Offered Spring. BIO 465/565 Cr.3NeurophysiologyAn examination of the nervous system beginning at the cellular level and working up to neuronal systems. Topics covered include the ionic basis of membrane potentials, synaptic communication, organization of functional circuits of neurons, and systems within the brain and/or spinal cord which control learning and memory, vision and motor function.

Exploration of these fundamental neurophysiology topics form the basis for understanding a variety of student-selected topics which will be covered later in the semester. Late-semester topics often include higher-order aspects of brain function or challenges to the nervous system, such as the repair of brain or spinal cord injury, degenerative disease states, dyslexia, or consciousness. /567 is an optional laboratory course which can be taken concurrently. This course is taught largely at an undergraduate level.

Graduate students will have additional course requirements/expectations. Prerequisite:, and either. Offered Spring. BIO 468/568 Cr.1Human Molecular Genetics LabA study of the techniques used in doing research in human molecular genetics with a focus on commonly used model organisms in the study of human genetic disorders.

Laboratory emphasis is on phenotype analysis, library screening, DNA microarray analysis, gene mapping, and bioinformatics. This course is taught largely at a graduate level. This lab is optional for those enrolled in /566.

/566 must be taken concurrently. Offered Fall. BIO 476/576 Cr.3Ecosystem EcologyEcosystems include the living and non-living components of an environmental system and have emergent properties that can only be understood by examining the system as a whole. This course will examine advanced ecological topics centered around the structure and function of aquatic and terrestrial ecosystems. Topics covered will include the development of the ecosystem concept, ecosystem succession, production/decomposition, energy transfer in food webs, and nutrient cycling.

The course will consist of classroom lectures, problem sets, and reading/discussion of relevant literature. This course is taught largely at an undergraduate level.

Graduate students will have additional course requirements/expectations. Prerequisite: and one semester of chemistry.

Offered Spring - Even Numbered Years. BIO 701 Cr.4Communication in the Biological SciencesThis course covers in detail the preparation and submission of scientific manuscripts for publication and the presentation of papers at scientific conferences. Topics covered include experimental design, preparation of manuscript sections, figures, and tables; writing with clarity, precision, and word economy; dealing with journal editors and reviewers; reviewing and editing of manuscripts; presentations at scientific conferences; preparation of visual aids; and communicating with the public, the press, and politicians. Offered Spring. BIO/MIC 714 Cr.3Advanced GeneticsThe application of molecular-genetic analysis to problems in modern biology. The course will cover the fundamentals of genetic analysis in both procaryotic and eucaryotic systems. Assigned readings from current literature will be discussed and evaluated.

A variety of topic areas will be considered including ecology, biotechnology, bioremediation, food science, medicine and basic research. Prerequisite: a previous course in genetics, microbial genetics, or molecular biology.

(Cross-listed with BIO/MIC; may only earn credit in one department.) Offered Spring - Odd Numbered Years. BIO 723 Cr.321st Century MycologyAn in-depth examination of contemporary research on fungi, including systematics and evolution, genetics, molecular ecology, biotechnology, bioremediation, physiology, plant or animal pathology, and/or developmental biology, through critical analysis and discussion of primary literature sources. Readings will exemplify major questions, experimental approaches, and methods, and will be analyzed to identify important contemporary research themes, paradigm shifts, and unanswered questions.

Prerequisite: /512;. Offered Occasionally.

BIO 779 Cr.1-2Biology Laboratory AssistantAllows graduate students to gain experience in assisting with preparation and teaching 300 and 400 level laboratory-based courses in conjunction with the regular instructor. Students will be expected to assist in preparation of course materials, demonstrate proper techniques, and evaluate students' performance. Repeatable for credit - maximum three. Prerequisite: graduate standing. Not applicable to students assisting in 100 or 200 level courses. Consent of instructor. Offered Fall, Spring.